Use this medication regularly in order to get the most benefit from it. People who are at high risk for becoming diabetic. Glucophage is from the biguanide class of oral anti-hyperglycemic agents. Metformin also increases your body's proper response to the insulin you naturally produce, and by decreasing the amount of glucose in your blood. Glucophage is from the biguanide class of oral anti-hyperglycemic agents. Metformin decreases the amount of sugar produced by cells in the liver. Glucophage is used to control blood sugar levels both between and directly after meals. Glucophage should be taken with meals.